Yuri Quintana
Chief, Division of Clinical Informatics Beth Israel Deaconess Medical Center
Seminars
Thursday 7th May 2026
From Narrative to Computable Signal: Building Longitudinal Data Architecture for Measurable Patient Engagement
9:30 am
- The problem is architecture, not ambition — Patient engagement data already exists inside most pharma and biotech organizations; the barrier to proving ROI is that it is unstructured, siloed, and not engineered for reuse as regulatory- or payer-grade evidence
- A practical three-step progression — The Outcome-Linked Maturity Model moves programs from vanity metrics (Level 1: counts and clicks) through clinical impact (Level 2: retention, recruitment) to decision-grade evidence (Level 3: RWE, regulatory submissions, HTA dossiers) using the LUMINA data architecture and FHIR/OMOP interoperability standards.
- No new systems required — only better structure — The Lean Technical Blueprint (Map → Standardize → Integrate → Enable AI → Measure) shows how to activate existing CRM, EDC, and EHR platforms through standard APIs, turning engagement from a cost center into a federated, portfolio-level asset aligned with outcomes
